FOSPHENYTOIN PRESCRIBING INFORMATION PDF
This resource may include information that has not been approved by the US Food and Drug Administration. For full prescribing information, including. Fosphenytoin official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. Medscape – Epilepsy dosing for Cerebyx (fosphenytoin), frequency-based adverse contraindications, pregnancy & lactation schedules, and cost information. be expressed as phenytoin sodium equivalents (PE) when prescribing; There is.
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Clarithromycin The metabolism of Fosphenytoin can be increased when combined with Clarithromycin. This has the potential to increase the frequency and severity of adverse events [see Warnings and Precautions 5. Formaldehyde is subsequently converted to formate, which is in informatio metabolized via a folate dependent mechanism. After administration of a loading dose, maintenance doses should be started at the next identified fosphenyfoin interval. CEREBYX should normally be gradually withdrawn to reduce the potential for increased seizure frequency and status epilepticus [see Warnings and Precautions 5.
Eltanolone The risk or severity of adverse effects can be increased when Fosphenytoin is combined with Eltanolone.
Mequitazine The metabolism of Fosphenytoin can be decreased when combined with Mequitazine. Isosorbide The metabolism of Isosorbide can be increased when combined with Fosphenytoin. Pregnancy Risk related to antiepileptic medicinal products in general When possible, medical advice regarding the potential risks to a foetus caused by both seizures and antiepileptic treatment should be given to all women of childbearing potential taking antiepileptic treatment, and especially to women planning pregnancy and women who are pregnant.
Alcuronium The risk or severity of adverse effects can prsscribing increased when Fosphenytoin is combined with Alcuronium. Diphenhydramine The metabolism of Fosphenytoin can be decreased when combined with Diphenhydramine.
To bookmark a medicine you must sign up and log in. Peak levels indicate an individual’s threshold for emergence of dose-related side effects and are obtained at the time of expected peak concentration.
Initial symptoms of acute phenytoin toxicity are nystagmus, ataxia, and dysarthria. Hesperetin The metabolism of Hesperetin can be increased when combined with Fosphenytoin. The product should not be stored at room temperature for more than 48 hours. Total exchange transfusion has been used in the treatment of severe intoxication in children.
HIGHLIGHTS OF PRESCRIBING INFORMATION
Dosing Errors Dosing errors associated with Pro-Epanutin have resulted in patients receiving the wrong dose of Pro-Epanutin. After opening, unused product should be discarded. Fosphenytoinn of the risks of cardiac and local toxicity associated with IV Fosphenytoin Sodium Injection, oral phenytoin should be used whenever possible. Methyltestosterone The metabolism of Fosphenytoin can be decreased when combined with Methyltestosterone.
Drugs that may either increase or decrease phenytoin serum levels. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: Fopshenytoin primrose oil The therapeutic efficacy of Fosphenytoin can be decreased when used in combination with Evening primrose oil.
Phenytoin may also cause increased serum levels of gamma glutamyl transpeptidase GGT. Children aged 5 years and older. See Table 6 for infusion times. Prescribihg The metabolism of Fosphenytoin can be decreased when combined with Crizotinib.
Fosphenytoin – DrugBank
Both treatments were administered for 5 days. Flurbiprofen The metabolism of Fosphenytoin can be decreased when combined with Flurbiprofen.
Monitoring of phenytoin serum levels is recommended when a drug interaction is suspected. Amiodarone The serum concentration of Amiodarone can be decreased when it is combined with Fosphenytoin. Fosphenytoin Rating No reviews – Add your review.
FOSPHENYTOIN SODIUM Injection mg PE in 2ml Vial mg PE in 10 ml Vial | Mylan
Eslicarbazepine The metabolism of Fosphenytoin can be increased when combined with Eslicarbazepine. A small percentage of individuals who have been treated with phenytoin the active metabolite of CEREBYX have been shown to metabolize the drug slowly. Bosentan The metabolism of Fosphenytoin can be increased when combined with Bosentan.
Please refer to Prdscribing for examples of dosing, dilution, and infusion time calculations. Rapid intravenous administration of Fosphenytoin Sodium Injection increases the risk of adverse cardiovascular reactions, including severe hypotension and cardiac arrhythmias. Flucloxacillin The metabolism of Fosphenytoin can be increased when combined with Flucloxacillin. Ivabradine The metabolism of Fosphenytoin can be decreased when combined with Ivabradine.
Clorazepate The metabolism of Fosphenytoin can be decreased when combined with Clorazepate. Captodiame The risk or severity of adverse effects can be increased when Fosphenytoin is precsribing with Captodiame.
Decreased serum concentrations of phenytoin the active metabolite of Fosphenytoin Sodium Injection may occur during pregnancy because of altered phenytoin pharmacokinetics [see Clinical Pharmacology